A paper test for occult blood in faeces using ortho-dianisidine.

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A paper test for occult blood in faeces using ortho-dianisidine.

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An ortho-tolidine hydrochloride test for the detection of occult blood in faeces without dietary restrictions.

The most widely used chemical test for occult blood involves the use of benzidine in one form or another. In the last few years it has been necessary to replace benzidine, because of its carcinogenic properties, by o-tolidine. Kohn and O'Kelly (1952, 1955) described an o-tolidine method for occult blood, but the patients must be on a meat-free diet or a very large number of false positive resul...

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An ortho-tolidine method for the detection of occult blood in faeces.

Benzidine is still the most commonly used reagent for occult blood tests in faeces. About three years ago, however, the manufacture of AnalaR benzidine in this country was discontinued as it was shown that benzidine has very marked carcinogenic properties, particularly in some of the stages of purification to AnalaR specification. This did not appear to be widely recognized probably because mos...

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Assessment of Routine Tests for Occult Blood in Faeces.

Routine chemical methods for the detection of occult blood in faeces depend on the peroxidase-like activity of haemoglobin and its iron-containing degradation products. The clinical value of these tests was first demonstrated by Boas (1901), using a method based on the guaiacum. test for blood described by van Deen (1861). Adler and Adler (1904) claimed that the colour reaction given by benzidi...

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The occult blood test.

The original occult blood tests were designed for forensic purposes, Schonbein and van Deen using a chemical test with guaiacum which was more sensitive than the older Teichmann's haemin crystal test. Subsequently similar chemical methods were widely used and in I893 Weber described his version of the guaiacum test for detecting occult blood in the faeces. Boas first made extensive use of this ...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1968

ISSN: 0021-9746

DOI: 10.1136/jcp.21.5.675